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Catalog No: OPCD01521
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OPCD01521
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Datasheets/ManualsPrintable datasheet for ATF3 Recombinant Protein (OPCD01521)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Met1-Ser181
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity>90%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolATF3
Gene Full Nameactivating transcription factor 3
Alias SymbolsActivating transcription factor 3;cAMP-dependent transcription factor ATF-3;cyclic AMP-dependent transcription factor ATF-3.
NCBI Gene Id467
Protein NameCyclic AMP-dependent transcription factor ATF-3
Description of TargetThis protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Uniprot IDP18847
Protein Accession #NP_001025458.1
Nucleotide Accession #NM_001030287.3
Protein Size (# AA)Met1~Ser181
Molecular Weight51kDa
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