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Catalog No: OAAQ00059
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OAAQ00059
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Datasheets/ManualsPrintable datasheet for OAAQ00059
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityMouse, Rat
Product FormatLiquid. 1X PBS, 0.09% NaN3, 0.2% BSA.
ClonalityMonoclonal
CloneATF2T71-G3
IsotypeRabbit IgG1k
HostRabbit
ConjugationAPC: Allophycocyanin
ApplicationFC
Reconstitution and Storage2-8C
ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Thr71 of human phospho ATF2
PurificationProtein A+G
Target Post-Translational ModificationPhospho-Thr71
Application InfoFor flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.
ReferenceShaulian E, and Karin M., (2002) Nat Cell Biol. 4:131-136.
Shimizu M, et al., (1998) Exp Cell Res. 239:93-103.
Lau E, and Ronai ZA. (2012) J Cell Sci. 125:2815-2824.
Bailey J, and Europe-Finner GN. (2005), J Mol Endocrinol. 34:19-35.
Raingeaud J, et al., (1995) J Biol Chem. 270:7420-7426.
Ouwens DM, et al., (2002) EMBO J. 21:3782-3793.
Livingstone C, et al., (1995) EMBO J. 1995,14:1785-97.
Yamasaki T, et al., (2009). J Biol Chem 284:8567-8581.
Lau E, et al., (2012) Cell 48:543-555.
Bhoumik A, et al., (2005) Mol Cell 18:577-587.
Gene SymbolATF2
Gene Full Nameactivating transcription factor 2
Alias SymbolsHB16, CREB2, TREB7, CREB-2, CRE-BP1
NCBI Gene Id1386
Protein Namecyclic AMP-dependent transcription factor ATF-2
Description of TargetThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene
Uniprot IDP15336
Protein Accession #NP_001243019.1
Nucleotide Accession #NM_001256090.1
  1. What is the species homology for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Mouse, Rat".

  2. How long will it take to receive "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)" provided in?

    This item is provided in "Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?

    This target may also be called "HB16, CREB2, TREB7, CREB-2, CRE-BP1" in publications.

  5. What is the shipping cost for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ATF2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ATF2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ATF2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ATF2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ATF2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ATF2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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