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Datasheets/Manuals | Printable datasheet for OAAQ00059 |
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Tested Species Reactivity | Human, Mouse |
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Predicted Species Reactivity | Mouse, Rat |
Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
Clonality | Monoclonal |
Clone | ATF2T71-G3 |
Isotype | Rabbit IgG1k |
Host | Rabbit |
Conjugation | APC: Allophycocyanin |
Application | FC |
Reconstitution and Storage | 2-8C |
Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr71 of human phospho ATF2 |
Purification | Protein A+G |
Target Post-Translational Modification | Phospho-Thr71 |
Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
Reference | Shaulian E, and Karin M., (2002) Nat Cell Biol. 4:131-136. Shimizu M, et al., (1998) Exp Cell Res. 239:93-103. Lau E, and Ronai ZA. (2012) J Cell Sci. 125:2815-2824. Bailey J, and Europe-Finner GN. (2005), J Mol Endocrinol. 34:19-35. Raingeaud J, et al., (1995) J Biol Chem. 270:7420-7426. Ouwens DM, et al., (2002) EMBO J. 21:3782-3793. Livingstone C, et al., (1995) EMBO J. 1995,14:1785-97. Yamasaki T, et al., (2009). J Biol Chem 284:8567-8581. Lau E, et al., (2012) Cell 48:543-555. Bhoumik A, et al., (2005) Mol Cell 18:577-587. |
Gene Symbol | ATF2 |
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Gene Full Name | activating transcription factor 2 |
Alias Symbols | HB16, CREB2, TREB7, CREB-2, CRE-BP1 |
NCBI Gene Id | 1386 |
Protein Name | cyclic AMP-dependent transcription factor ATF-2 |
Description of Target | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene |
Uniprot ID | P15336 |
Protein Accession # | NP_001243019.1 |
Nucleotide Accession # | NM_001256090.1 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Mouse, Rat".
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How long will it take to receive "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)" provided in?
This item is provided in "Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?
This target may also be called "HB16, CREB2, TREB7, CREB-2, CRE-BP1" in publications.
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What is the shipping cost for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Human ATF2 Antibody : APC (Phospho-Thr71) (OAAQ00059)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ATF2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ATF2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ATF2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ATF2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ATF2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ATF2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.