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ATF1 Antibody - C-terminal region (ARP97646_P050)

100 ul
$289.00
In Stock
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Gene Symbol:
ATF1
Official Gene Full Name:
activating transcription factor 1
NCBI Gene Id:
466
Protein Name:
cyclic AMP-dependent transcription factor ATF-1
Swissprot Id:
P16220-3
Protein Accession #:
NP_005162.1
Nucleotide Accession #:
NM_005171.4
Alias Symbols:
TREB36, EWS-ATF1, FUS/ATF-1
Description of Target:
This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
Protein Size (# AA):
230
Molecular Weight:
25 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ATF1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ATF1.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human ATF1
Predicted Species Reactivity:
Human
Tested Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: KNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSNKSV
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-ATF1 (ARP97646_P050) antibody is Catalog # AAP97646
Datasheets/Manuals:
Printable datasheet for anti-ATF1 (ARP97646_P050) antibody

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