Aviva Systems Biology will be closed in observance of Good Friday 3/29/2024. If you are in need of any assistance please email info@avivasysbio.com

Catalog No: OASE00321-Biotin
Size:100ug
Price: $429.00
SKU
OASE00321-Biotin
Availability: Domestic: within 3-5 days delivery | International: 3-5 days
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.

Ataxin 1 Antibody : Biotin (OASE00321-Biotin)

Datasheets/ManualsPrintable datasheet for OASE00321-Biotin
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityMonoclonal
CloneS65-37
Isotype IgG1
HostMouse
ConjugationBiotin
ApplicationWB, ICC
Additional InformationBackground Info: Detects a 85 kDa protein. No cross-reactivity against phosphor S751-Ataxin-1. Minimal cross-reactivity against S751A mutant of Ataxin-1 by ELISA and immunofluorescence and negative by immunoblot.
::Scientific Background: Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons.
::Certificate of Analysis: 1ug/mL was sufficient for detection of Ataxin 1 in 20 ug of COS cells transiently transfected with Ataxin-1 lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenSynthetic peptide amino acids 746-761(RKRRRWSAPETRKLEK) of mouse ataxin-1 (accession no. P54254)
Rat: 93% identity (15/16 amino
acids identical)
Human: 87% identity (14/16 amino acids identical)
PurificationProtein G Purified
Concentration1 mg/ml
Dilution1:1000 WB
Storage BufferPBS pH 7.4, 50% glycerol, 0.1% sodium azide
Gene SymbolAtxn1
Gene Full Nameataxin 1
Alias SymbolsSc, Atx, Atx1, Sca1, C85907, Gm10786, 2900016G23Rik
NCBI Gene Id20238
Uniprot IDP54254
Protein Accession #NP_001186233.1
  1. What is the species homology for "Ataxin 1 Antibody : Biotin (OASE00321-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "Ataxin 1 Antibody : Biotin (OASE00321-Biotin)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "Ataxin 1 Antibody : Biotin (OASE00321-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Ataxin 1 Antibody : Biotin (OASE00321-Biotin)"?

    This target may also be called "Sc, Atx, Atx1, Sca1, C85907, Gm10786, 2900016G23Rik" in publications.

  5. What is the shipping cost for "Ataxin 1 Antibody : Biotin (OASE00321-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Ataxin 1 Antibody : Biotin (OASE00321-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Ataxin 1 Antibody : Biotin (OASE00321-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Ataxin 1 Antibody : Biotin (OASE00321-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ATXN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ATXN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ATXN1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ATXN1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ATXN1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ATXN1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:Ataxin 1 Antibody : Biotin (OASE00321-Biotin)
Your Rating
We found other products you might like!