ASF1B Antibody - middle region (ARP46276_P050)

Catalog No: ARP46276_P050

WB Suggested Anti-ASF1B Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysateASF1B is supported by BioGPS gene expression data to be expressed in Jurkat

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASF1B
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%; Zebrafish: 86%
• Peptide Sequence: Synthetic peptide located within the following region: YHGQEFIRVGYYVNNEYLNPELRENPPMKPDFSQLQRNILASNPRVTRFH
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ASF1B (ARP46276_P050) antibody is Catalog # AAP46276 (Previous Catalog # AAPS17611)
• Sample Type Confirmation:

  ASF1B is supported by BioGPS gene expression data to be expressed in Jurkat

• Reference: Brandenberger,R., (2004) Nat. Biotechnol. 22 (6), 707-716

Target Info

• Gene Symbol: ASF1B
• Gene Full Name: ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
• Alias Symbols: CIA-II
• NCBI Gene Id: 55723
• Protein Name: Histone chaperone ASF1B
• Description of Target: ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.
• Uniprot ID: Q9NVP2
• Protein Accession #: NP_060624
• Nucleotide Accession #: NM_018154
• Protein Size (# AA): 202
• Molecular Weight: 22kDa
• Protein Interactions: UBC; HIST3H3; H3F3A; MMS22L; TONSL; MCM6; HIST4H4; HIST1H3A; KHSRP; IDH1; CDAN1; IPO4; ASF1A; HIST1H3C; TLK2; HIST1H3E; MCM2; HAT1; RBBP7; CHAF1B; HIRA; UL30; UL52; HCFC1; C15orf41; TLK1; HIST1H4F; HIST1H3B; CHAF1A; H3F3B; TAF1; MRPS7; UBXN1; DOK2; HIST1H