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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for ASCL1 Antibody (OACD01808) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot |
| Reconstitution and Storage | 2°C to 8°C|-20°C |
| Immunogen | Recombinant ASCL1 (Lys84~Phe326) expressed in E.coli |
| Purification | Affinity Purified; Protein A Purified |
| Concentration | 0.5 mg/ml |
| Specificity | The antibody is a rabbit polyclonal antibody raised against ASCL1. It has been selected for its ability to recognize ASCL1 in immunohistochemical staining and western blotting. |
| Source | Polyclonal antibody preparation |
| Application Data | WB: 0.5-2 ug/mL IHC: 5-20 ug/mL ICC: 5-20 ug/mL |
| Gene Symbol | ASCL1 |
|---|---|
| Gene Full Name | achaete-scute family bHLH transcription factor 1 |
| Alias Symbols | achaete scute protein;achaete-scute complex homolog 1;achaete-scute complex-like 1;achaete-scute homolog 1;ASH1;ASH-1;bHLHa46;class A basic helix-loop-helix protein 46;HASH1;MASH1. |
| NCBI Gene Id | 429 |
| Protein Name | Achaete-scute homolog 1 |
| Description of Target | Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. Directly binds the E box motif (5'-CANNTG-3') on promoters and promotes transcription of neuronal genes. The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. |
| Uniprot ID | P50553 |
| Protein Accession # | NP_004307.2 |
| Nucleotide Accession # | NM_004316 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ASCL1 Antibody (OACD01808)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "ASCL1 Antibody (OACD01808)"?
This item is available "Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery".
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What buffer format is "ASCL1 Antibody (OACD01808)" provided in?
This item is provided in "Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ASCL1 Antibody (OACD01808)"?
This target may also be called "achaete scute protein;achaete-scute complex homolog 1;achaete-scute complex-like 1;achaete-scute homolog 1;ASH1;ASH-1;bHLHa46;class A basic helix-loop-helix protein 46;HASH1;MASH1." in publications.
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What is the shipping cost for "ASCL1 Antibody (OACD01808)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ASCL1 Antibody (OACD01808)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ASCL1 Antibody (OACD01808)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ASCL1 Antibody (OACD01808)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ASCL1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ASCL1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ASCL1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ASCL1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ASCL1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ASCL1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
