Size:100 ul
$249.00
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SKU
ARP32355_T100
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Conjugation Options

ARP32355_T100-FITC Conjugated

ARP32355_T100-HRP Conjugated

ARP32355_T100-Biotin Conjugated

ASCL1 Antibody - N-terminal region (ARP32355_T100)

Catalog#: ARP32355_T100
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-13219 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ASCL1
Purification Protein A purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 92%; Guinea Pig: 100%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%
Complete computational species homology data Anti-ASCL1 (ARP32355_T100)
Peptide Sequence Synthetic peptide located within the following region: QSAQQQQQQQQQQQQAPQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELM
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-ASCL1 (ARP32355_T100) antibody is Catalog # AAP32355 (Previous Catalog # AAPP03344)
Datasheets/Manuals Printable datasheet for anti-ASCL1 (ARP32355_T100) antibody
Target Reference Somasundaram,K., et al., (2005) Oncogene. 24(47), 7073-83
Publications

Suozzi, A., Malatesta, M. & Zancanaro, C. Subcellular distribution of key enzymes of lipid metabolism during the euthermia-hibernation-arousal cycle. J. Anat. 214, 956-62 (2009). IHC, WB, Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat 19538638

Vias, M. et al. Pro-neural transcription factors as cancer markers. BMC Med. Genomics 1, 17 (2008). IHC, WB, Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat 18489756

Gene Symbol ASCL1
Official Gene Full Name Achaete-scute complex homolog 1 (Drosophila)
Alias Symbols ASH1, HASH1, MASH1, bHLHa46
NCBI Gene Id 429
Protein Name Achaete-scute homolog 1
Description of Target ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers.
Swissprot Id P50553
Protein Accession # NP_004307
Nucleotide Accession # NM_004316
Protein Size (# AA) 236
Molecular Weight 25kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ASCL1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ASCL1.
Protein Interactions MEF2D; MEF2C; MEF2A; NEUROG2; UBQLN1; EP300; TCF4; BMP2; ASCL1;
  1. What is the species homology for "ASCL1 Antibody - N-terminal region (ARP32355_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat".

  2. How long will it take to receive "ASCL1 Antibody - N-terminal region (ARP32355_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ASCL1 Antibody - N-terminal region (ARP32355_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ASCL1 Antibody - N-terminal region (ARP32355_T100)"?

    This target may also be called "ASH1, HASH1, MASH1, bHLHa46" in publications.

  5. What is the shipping cost for "ASCL1 Antibody - N-terminal region (ARP32355_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ASCL1 Antibody - N-terminal region (ARP32355_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ASCL1 Antibody - N-terminal region (ARP32355_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "25kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ASCL1 Antibody - N-terminal region (ARP32355_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "ASCL1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ASCL1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ASCL1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ASCL1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ASCL1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ASCL1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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