Catalog No: ARP67972_P050
Price: $0.00
SKU
ARP67972_P050
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Datasheets/ManualsPrintable datasheet for anti-ASAP2 (ARP67972_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N-terminal region of Human ASAP2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceDog: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 78%; Rat: 93%; Zebrafish: 93%
Peptide SequenceSynthetic peptide located within the following region: LSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQ
Concentration0.5 mg/ml
Blocking PeptideFor anti-ASAP2 (ARP67972_P050) antibody is Catalog # AAP67972
Gene SymbolASAP2
Alias SymbolsPAP, PAG3, AMAP2, DDEF2, SHAG1, CENTB3, Pap-alpha
NCBI Gene Id8853
Protein NameArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2
Description of TargetThis gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport.
Uniprot IDO43150
Protein Accession #NP_003878
Nucleotide Accession #NM_003887
Protein Size (# AA)1006
Molecular Weight112kDa
Protein InteractionsSH3KBP1; MAP1LC3A; CTTN; Asap1; IKBKG; UBC; SUMO1; ELAVL1; ITSN1; THSD7A; GRB2; PACSIN3; PXN; BIN1; PTK2B; RAN; ARF6; REPS2; ARF5; ARF1; SRC; TBRG4;
  1. What is the species homology for "ASAP2 Antibody - N-terminal region (ARP67972_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish".

  2. How long will it take to receive "ASAP2 Antibody - N-terminal region (ARP67972_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ASAP2 Antibody - N-terminal region (ARP67972_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ASAP2 Antibody - N-terminal region (ARP67972_P050)"?

    This target may also be called "PAP, PAG3, AMAP2, DDEF2, SHAG1, CENTB3, Pap-alpha" in publications.

  5. What is the shipping cost for "ASAP2 Antibody - N-terminal region (ARP67972_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ASAP2 Antibody - N-terminal region (ARP67972_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ASAP2 Antibody - N-terminal region (ARP67972_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "112kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ASAP2 Antibody - N-terminal region (ARP67972_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ASAP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ASAP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ASAP2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ASAP2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ASAP2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ASAP2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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