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ARX antibody - middle region (ARP36824_T100)

100 ul
$249.00
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Conjugation Options

ARP36824_T100-FITC Conjugated

ARP36824_T100-HRP Conjugated

ARP36824_T100-Biotin Conjugated

Gene Symbol:
ARX
NCBI Gene Id:
11878
Official Gene Full Name:
Aristaless related homeobox
Protein Name:
Homeobox protein ARX
Swissprot Id:
O35085
Protein Accession #:
NP_031518
Nucleotide Accession #:
NM_007492
Replacement Item:
This antibody may replace item sc-130695 from Santa Cruz Biotechnology.
Description of Target:
ARX (Aristaless-related genes), a subset of the Paired-related homeobox genes, is a group of regulators of essential events during vertebrate embryogenesis. Arx was highly conserved between mouse and zebrafish. Studies have disclosed its neuromeric expression in the forebrain and longitudinal expression in the floor plate in mouse and zebrafish. It is also expressed in the dorsal telencephalon (presumptive cerebral cortex) of mouse embryos.
Protein Size (# AA):
564
Molecular Weight:
58kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ARX.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ARX.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of mouse ARX
Tested Species Reactivity:
Human, Mouse
Predicted Homology Based on Immunogen Sequence:
Dog: 93%; Guinea Pig: 93%; Horse: 79%; Human: 93%; Mouse: 100%; Rabbit: 93%; Rat: 93%
Complete computational species homology data:
Anti-ARX (ARP36824_T100)
Peptide Sequence:
Synthetic peptide located within the following region: TGAEDDEEELLEDEEDEEEEEELLEDDDEELLEDDARALLKEPRRCSVAT
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-ARX (ARP36824_T100) antibody is Catalog # AAP36824 (Previous Catalog # AAPP09069)
Datasheets/Manuals:
Printable datasheet for anti-ARX (ARP36824_T100) antibody
Target Reference:
Hirata,T., et al., (2006) Development 133 (8), 1433-1443
Publications:

Condomines, M. et al. Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma. J. Immunol. 183, 832-40 (2009). WB, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 19542363

Price, M. G. et al. A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment. J. Neurosci. 29, 8752-63 (2009). WB, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 19587282

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