Catalog No: OPCD01482
Price: $0.00
SKU
OPCD01482
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Datasheets/Manuals | Printable datasheet for ARNT Recombinant Protein (OPCD01482) |
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Predicted Species Reactivity | Homo sapiens|Human |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Gln624-Glu789 |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | >95% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | ARNT |
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Gene Full Name | aryl hydrocarbon receptor nuclear translocator |
Alias Symbols | aryl hydrocarbon receptor nuclear translocator;bHLHe2;class E basic helix-loop-helix protein 2;dioxin receptor, nuclear translocator;HIF1B;HIF1-beta;HIF-1beta;HIF-1-beta;HIF1BETA;hypoxia-inducible factor 1, beta subunit;Hypoxia-inducible factor 1-beta;TANGO. |
NCBI Gene Id | 405 |
Protein Name | Aryl hydrocarbon receptor nuclear translocator |
Description of Target | Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409). |
Uniprot ID | P27540 |
Protein Accession # | NP_001184254.1 |
Nucleotide Accession # | NM_001197325.1 |
Protein Size (# AA) | Gln624~Glu789 |
Molecular Weight | 23kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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