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Catalog No: OPCD00730
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OPCD00730
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Datasheets/ManualsPrintable datasheet for ARHGEF7 Recombinant Protein (OPCD00730)
Product Info
Predicted Species ReactivityRat|Rattus norvegicus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Met1-Ala188
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolArhgef7
Gene Full NameRho guanine nucleotide exchange factor 7
Alias Symbolsbeta-Pix;P85spr;Pak3bp;PAK-interacting exchange factor beta;Rho guanine nucleotide exchange factor (GEF) 7;rho guanine nucleotide exchange factor 7.
NCBI Gene Id114559
Protein NameRho guanine nucleotide exchange factor 7
Description of TargetActs as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons (By similarity).
Uniprot IDO55043
Protein Accession #NP_001106994.1
Nucleotide Accession #NM_001113522.1
Protein Size (# AA)Met1~Ala188
Molecular Weight25kDa
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