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Catalog No: OASG05888
Size:100 uL
Price: $239.00
SKU
OASG05888
Availability: Domestic: within 2-3 weeks delivery | International: 2-3 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-ARHGEF7 (OASG05888) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB, IHC
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenSynthesized peptide derived from the Internal region of human PIXBeta. Location: 280-360aa.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
SpecificityPIXBeta Polyclonal Antibody detects endogenous levels of PIXBeta protein.
Application InfoWB 1:500~2000
IHC 1:100~300
ELISA 1:5000
Publications

Platelet-derived growth factor receptor-a and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 313, L1174-L1187 (2017). 28775097

Description
Gene SymbolARHGEF7
Gene Full NameRho guanine nucleotide exchange factor (GEF) 7
Alias SymbolsP50, P85, PAK3, PIXB, COOL1, P50BP, COOL-1, P85SPR, BETA-PIX, P85COOL1, Nbla10314
NCBI Gene Id8874; 54126; 114559
Description of TargetRho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Uniprot IDQ14155, Q9ES28, O55043
Molecular Weight75/80 kDa
  1. What is the species homology for "ARHGEF7 Antibody - middle region (OASG05888)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "ARHGEF7 Antibody - middle region (OASG05888)"?

    This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".

  3. What buffer format is "ARHGEF7 Antibody - middle region (OASG05888)" provided in?

    This item is provided in "Liquid. PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ARHGEF7 Antibody - middle region (OASG05888)"?

    This target may also be called "P50, P85, PAK3, PIXB, COOL1, P50BP, COOL-1, P85SPR, BETA-PIX, P85COOL1, Nbla10314" in publications.

  5. What is the shipping cost for "ARHGEF7 Antibody - middle region (OASG05888)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ARHGEF7 Antibody - middle region (OASG05888)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ARHGEF7 Antibody - middle region (OASG05888)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "75/80 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ARHGEF7 Antibody - middle region (OASG05888)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ARHGEF7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ARHGEF7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ARHGEF7"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ARHGEF7"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ARHGEF7"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ARHGEF7"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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