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ARHGAP4 Antibody (OAGA00224)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
ICC, IF, IHC-FFPE, WB
Additional Information:
Background: This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
:::
Positive Controls: Jurkat, NT2D1
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Cellular Localization: Cytoplasm
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item:
This antibody may replace item sc-131400 from Santa Cruz Biotechnology.
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 280 of ARHGAP4 (Uniprot ID#P98171)
Purification:
Purified by antigen-affinity chromatography.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-ARHGAP4 antibody - OAGA00224
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol:
ARHGAP4
Official Gene Full Name:
Rho GTPase-activating protein 4
Alias Symbols:
C1 antibody, KIAA0131 antibody, RGC1 antibody, RhoGAP4 antibody, SrGAP4 antibody, p115 antibody, ARHGAP4 antibody, rho-type GTPase-activating protein 4 antibody, Rho-GAP hematopoietic protein C1 antibody, rho GTPase-activating protein 4 antibody, Rho GTPa
NCBI Gene Id:
393
Protein Name:
Rho GTPase-activating protein 4
Swissprot Id:
P98171
Protein Accession #:
NP_001158213.1
Molecular Weight:
105 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ARHGAP4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ARHGAP4.

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