ARFGAP1 Antibody - middle region (ARP57149_P050)

Catalog No: ARP57149_P050

WB Suggested Anti-ARFGAP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARFGAP1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
• Peptide Sequence: Synthetic peptide located within the following region: GQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ARFGAP1 (ARP57149_P050) antibody is Catalog # AAP57149 (Previous Catalog # AAPP40741)

Target Info

• Gene Symbol: ARFGAP1
• Gene Full Name: ADP-ribosylation factor GTPase activating protein 1
• Alias Symbols: ARF1GAP, HRIHFB2281
• NCBI Gene Id: 55738
• Protein Name: ADP-ribosylation factor GTPase-activating protein 1
• Description of Target: The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: Q8N6T3
• Protein Accession #: NP_060679
• Nucleotide Accession #: NM_018209
• Protein Size (# AA): 406
• Molecular Weight: 45kDa
• Protein Interactions: KRTAP10-9; KRTAP9-2; KRTAP3-2; GABARAPL2; GRN; FOS; TRIM23; UBC; RPL22; HK1; RAD52; RPL11; RFC3; PRKACB; APOE; APOC3; APOB; ASB10; RASIP1; RAB23; COPS5; MED27; REEP5; APP; LRRK2; MAP1LC3B; TK1; SMN1; TMED2; CYTH2; COPA; CSNK1D; RGS2; KDELR1; ARF1;