ARCN1 Antibody - middle region (OAAB13082)

Catalog No: OAAB13082

Size:400ul

ARCN1 Antibody (Center) (Cat. # OAAB13082) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ARCN1 antibody detected the ARCN1 protein (arrow).

ARCN1 is strongly supported by BioGPS gene expression data to be expressed in ZR75-1

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
• Additional Information: Precautions: ARCN1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity)
  Cellular Location: Cytoplasm (By similarity). Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (By similarity)
  Tissue Location: Ubiquitously expressed.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This ARCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human ARCN1.
• Predicted Homology Based on Immunogen Sequence: Cow; Human; Mouse; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  ARCN1 is strongly supported by BioGPS gene expression data to be expressed in ZR75-1

• Application Info: WB: 1:1000

Target Info

• Gene Symbol: ARCN1
• Alias Symbols: COPD, SRMMD
• NCBI Gene Id: 372
• Protein Name: Coatomer subunit delta
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P48444
• Protein Accession #: NP_001135753.1
• Molecular Weight: 57210 Da