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AQR Antibody - C-terminal region (ARP64428_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP64428_P050-FITC Conjugated

ARP64428_P050-HRP Conjugated

ARP64428_P050-Biotin Conjugated

Gene Symbol:
AQR
Official Gene Full Name:
Aquarius homolog (mouse)
NCBI Gene Id:
9716
Protein Name:
Intron-binding protein aquarius
Swissprot Id:
O60306
Protein Accession #:
NP_055506
Nucleotide Accession #:
NM_014691
Alias Symbols:
DKFZp686B23123, IBP160, KIAA0560, fSAP164
Replacement Item:
This antibody may replace item sc-167110 from Santa Cruz Biotechnology.
Description of Target:
AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Protein Size (# AA):
1485
Molecular Weight:
171kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express AQR.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express AQR.
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Human AQR
Predicted Species Reactivity:
Horse, Human
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Horse: 79%; Human: 100%
Complete computational species homology data:
Anti-AQR (ARP64428_P050)
Peptide Sequence:
Synthetic peptide located within the following region: DTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; LGR4; SUZ12; RNF2; BMI1; ZNF830; WDR83; WDR77; RBM22; PQBP1; RBM4; EIF4A3; MAGOH; SIRT7; HNRNPA1; Prpf8; Cdc5l; Snw1; USP28;
Blocking Peptide:
For anti-AQR (ARP64428_P050) antibody is Catalog # AAP64428
Datasheets/Manuals:
Printable datasheet for anti-AQR (ARP64428_P050) antibody
Sample Type Confirmation:

AQR is supported by BioGPS gene expression data to be expressed in MCF7

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