Aprotinin - Aprotinin Protein (OPPA01202)

Catalog No: OPPA01202 (Formerly GWB-D1033E)

Size:100mg

Product Info

• Product Format: Lyophilized. Sterile filtered white powder with no additives.
• Additional Information: Chemical Formula: C₂₈₄H₄₃₂N₈₄O₇₉S₇
• Reconstitution and Storage: Reconstitution: It is recommended to reconstitute the lyophilized Aprotinin in sterile 18M Omega -cm H₂O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
  Storage: Lyophilized Aprotinin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution, Aprotinin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
• Concentration: 1 mg/ml (prior to lyoph)
• Purity: Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Biological Activity: 6,120 KIU (Kallikrein Inactivator Units) per mg, 3.4 pH.Eur.U/mg.
• Source: Bovine Lung

Target Info

• Gene Symbol: Aprotinin
• Alias Symbols: BPI, BPTI
• NCBI Gene Id: 404172
• Protein Name: Pancreatic trypsin inhibitor
• Description of Target: Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b).
• Uniprot ID: P00974
• Molecular Weight: 6512 Da