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APP Antibody (OAPB00876)

0.1 mg
$375.00
In Stock
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Conjugation Options

OAPB00876-FITC Conjugated

OAPB00876-HRP Conjugated

OAPB00876-Biotin Conjugated

Gene Symbol:
App
NCBI Gene Id:
11820
Protein Name:
Amyloid beta A4 protein
Swissprot Id:
P12023
Alias Symbols:
Ag, Abpp, Adap, Cvap, Abeta, betaApp, E030013M08Rik,
Replacement Item:
This antibody may replace item sc-117075 from Santa Cruz Biotechnology.
Description of Target:
(NT2) Amyloid precursor protein
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity chromatography purified via peptide column
Application:
ELISA, WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express App.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express App.
Immunogen:
The immunogen for anti-APP antibody: antibody was raised against an 18 amino acid peptide near the amino terminus of human APP.
Predicted Species Reactivity:
Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Human; Mouse; Rat
Reconstitution and Storage:
APP antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Blocking Peptide:
For anti-APP antibody is Catalog # OEPB03000
Datasheets/Manuals:
Printable datasheet for anti-APP antibody - OAPB00876
Application Info:
APP antibody can be used for detection of APP by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
:::
Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Target Reference:
Ponte P, Gonzalez-DeWhitt P, Schilling J, et al. A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature1988; 331:525-77.;Selkoe DJ. Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease. Annu Rev Cell Biol1994; 10:373-403.;Nikolaev A, McLaughlin T, O’Leary DD, et al. APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature2009; 457:981-9.;

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