Apobec1 Antibody - N-terminal region (OAAB09828)

Catalog No: OAAB09828

Size:400ul

The anti-Apobec1 N-term Pab (Cat. #OAAB09828) is used in Western blot to detect Apobec in mouse small intestine tissue lysate.

Western blot analysis of anti-Apobec1 Antibody (N-term) (Cat.#OAAB09828) in 293 cell line lysates (35ug/lane). Apobec1(arrow) was detected using the purified Pab (1:60dilution).

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: Apobec1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation
  Cellular Location: Cytoplasm.
  Tissue Location: Expressed exclusively in the small intestine.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This Apobec1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human Apobec1.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: APOBEC1
• Alias Symbols: BEDP, HEPR, CDAR1, APOBEC-1
• NCBI Gene Id: 339
• Protein Name: C->U-editing enzyme APOBEC-1
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P41238
• Protein Accession #: NP_001635.2
• Molecular Weight: 28192 Da