APLP2 Antibody (OAAF03276)

Catalog No: OAAF03276 (Formerly GWB-ASE352)

Size:100 ug

Western blot analysis of extracts from RAW264.7/A549 cells, using APLP2 Antibody. The lane on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human APLP2.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: APLP2 antibody detects endogenous levels of total APLP2 protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: WB: 1:500~1:3000; ELISA: 1:40000
• Reference: Sprecher C.A., Biochemistry 32:4481-4486(1993).
  Wasco W., Nat. Genet. 5:95-99(1993).
  von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).

Target Info

• Gene Symbol: APLP2
• Gene Full Name: amyloid beta precursor like protein 2
• Alias Symbols: amyloid beta (A4) precursor-like protein 2;amyloid precursor protein homolog HSD-2;Amyloid protein homolog;amyloid-like protein 2;APLP-2;APPH;APPL2;CDEBP;CDEI box-binding protein;testicular tissue protein Li 23.
• NCBI Gene Id: 334
• Protein Name: Amyloid-like protein 2
• Description of Target: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).
• Uniprot ID: Q06481
• Protein Accession #: NP_001135748.1
• Molecular Weight: 86 kDa