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APEX1 Antibody (OACA02420)

100 ug
$315.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IHC, CHIP
Reconstitution and Storage:
Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement Item:
This antibody may replace item sc-159150 from Santa Cruz Biotechnology.
Immunogen:
Recombinant Human DNA-(apurinic or apyrimidinic site) lyase Protein
Purification:
Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence:
Human, Mouse
Datasheets/Manuals:
Printable datasheet for anti-APEX1 (OACA02420) antibody
Specificity:
Human
Formulation:
Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Gene Symbol:
APEX1
Official Gene Full Name:
APEX nuclease (multifunctional DNA repair enzyme) 1
Alias Symbols:
APE, APX, APE1, APEN, APEX, HAP1, REF1
NCBI Gene Id:
328
Protein Name:
DNA-(apurinic or apyrimidinic site) lyase
Description of Target:
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Swissprot Id:
P27695
Protein Accession #:
NP_001231178.1
Nucleotide Accession #:
NM_001244249.1
Protein Size (# AA):
318
Molecular Weight:
36 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express APEX1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express APEX1.

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