APCS Antibody (OABB01492)

Catalog No: OABB01492

Size:100UG

Anti-Serum Amyloid P Picoband antibody
All lanes: Anti-Serum Amyloid P(OABB01492) at 0.5ug/ml
WB: Recombinant Mouse Serum Amyloid P Protein 0.5ng
Predicted bind size: 39 kDa
Observed bind size: 39 kDa

Anti-Serum Amyloid P Picoband antibody
IHC(P): Mouse Kidney Tissue

Product Info

• Tested Species Reactivity: Mouse
• Predicted Species Reactivity: Mouse|Rat
• Product Format: Lyophilized. Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
• Clonality: Polyclonal
• Clone: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: ELISA, IHC, WB
• Additional Information: Notes: Tested Species: In-house tested species with positive results.
  By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
  Other applications have not been tested.
  Optimal dilutions should be determined by end users.
  
  Background: Amyloid P component, serum(SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component(AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened beta-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
• Reconstitution and Storage: 2°C to 8°C|-20°C
• Immunogen: E.coli-derived mouse Serum Amyloid P recombinant protein (Position: Q21-D224). Mouse Serum Amyloid P shares 70% and 80% amino acid (aa) sequences identity with human and rat Serum Amyloid P, respectively.
• Purification: Affinity Purified
• Concentration: 500 ug/ml
• Specificity: No cross reactivity with other proteins.
• Application Info: Western blot: 0.1-0.5 ug/ml: Mouse
  Immunohistochemistry (Paraffin-embedded Section): 0.5-1 ug/ml: Mouse: By Heat
  ELISA : 0.1-0.5 ug/ml: Mouse
• Storage Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Target Info

• Gene Symbol: Apcs
• Gene Full Name: amyloid P component, serum
• Alias Symbols: APCS amyloid P-component serum protein;Sap;serum amyloid P-component.
• NCBI Gene Id: 20219
• Protein Name: Serum amyloid P-component
• Description of Target: Serum amyloid P-component
• Uniprot ID: P12246
• Molecular Weight: 26247 MW