APBB1IP Antibody - C-terminal region (OABB01109)

Catalog No: OABB01109

Size:100UG

Anti-RIAM antibody, OABB01109, Western blotting
Lane 1: Rat Thymus Tissue Lysate
Lane 2: Rat Spleen Tissue Lysate
Lane 3: Rat RAJI Tissue Lysate
Lane 4: HL-60 Cell Lysate

Anti-RIAM antibody, OABB01109, IHC(P)
IHC(P): Human Tonsil Tissue

Anti-RIAM antibody, OABB01109, ICC
ICC: JURKAT Cell

Product Info

• Tested Species Reactivity: Human, Mouse, Rat
• Predicted Species Reactivity: Hamster|Human|Mouse|Rat
• Product Format: Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Clonality: Polyclonal
• Clone: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Frozen|Western blot
• Additional Information: Notes: Tested Species: In-house tested species with positive results.
  Predicted Species: Species predicted to be fit for the product based on sequence similarities.
  By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
  Other applications have not been tested.
  Optimal dilutions should be determined by end users.
  
  Background: APBB1IP(APBB1-Interacting Protein), also called RIAM or RARP1, is a protein that in humans is encoded by the APBB1IP gene. By genomic sequence analysis, Lafuente et al.(2004) mapped the RIAM gene to chromosome 10p12.1. Using promoter-reporter gene assays, Inagaki et al.(2003) found that RARP1 suppressed transcription from AP1 and SRE sites, but not CRE sites, in all cell lines examined. The proline-rich regions of RARP1 suppressed AP1 transactivation. Lafuente et al.(2004) found that RIAM interacted with profilin and VASP, molecules that regulate actin dynamics, as well as with RAP1-GTP.
• Reconstitution and Storage: 2°C to 8°C|-20°C
• Immunogen: Polypeptide
• Purification: Affinity Purified
• Concentration: 500 ug/ml
• Specificity: No cross reactivity with other proteins.
• Application Info: Western blot: 0.1-0.5 ug/ml: Human, Mouse, Rat
  Immunohistochemistry (Paraffin-embedded Section): 0.5-1 ug/ml: Human, Rat: By Heat
  Immunohistochemistry (Frozen Section): 0.5-1 ug/ml: Rat
  Immunocytochemistry: 0.5-1 ug/ml: Human
  Immunocytochemistry/Immunofluorescence: 5 ug/ml: Human
  Flow Cytometry: 1-3 ug/1x10^6 cells: Human
• Storage Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Description: Rabbit IgG polyclonal antibody for Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(APBB1IP) detection. Tested with WB, IHC-P, IHC-F, ICC, ICC/IF, FCM in Human;Mouse;Rat.

Target Info

• Gene Symbol: APBB1IP
• Gene Full Name: amyloid beta precursor protein binding family B member 1 interacting protein
• Alias Symbols: amyloid beta A4 precursor protein-binding family B member 1-interacting protein;APBB1-interacting protein 1;INAG1;PREL1;PREL-1;proline rich EVH1 ligand 1;Proline-rich EVH1 ligand 1;proline-rich protein 73;rap1-GTP-interacting adapter molecule;Rap1-GTP-interacting adaptor molecule;Rap1-interacting adaptor molecule;RARP1;RARP-1;retinoic acid-responsive proline-rich protein 1;RIAM.
• NCBI Gene Id: 54518
• Protein Name: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
• Description of Target: Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
• Uniprot ID: Q7Z5R6
• Molecular Weight: 73183 MW