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Catalog No: OACD01660
Price: $0.00
SKU
OACD01660
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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Datasheets/ManualsPrintable datasheet for ANXA1 Antibody (OACD01660)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationImmunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Reconstitution and Storage2°C to 8°C|-20°C
ImmunogenRange: Glu6 - Asn346
PurificationAffinity Purified; Protein A Purified
Concentration0.5 mg/ml
Preservative0.02% NaN3
SpecificityThe antibody is a rabbit polyclonal antibody raised against ANXA1. It has been selected for its ability to recognize ANXA1 in immunohistochemical staining and western blotting.
FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Application DataWestern blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5,000
Optimal working dilutions must be determined by end user.
Gene SymbolAnxa1
Gene Full Nameannexin A1
Alias Symbolsannexin A1;annexin I;annexin-1;Anx;Anx-1;Anx-A1;C430014K04Rik;calpactin II;calpactin-2;chromobindin-9;lipocortin 1;lipocortin I;Lp;Lpc;Lpc1;Lpc-1;p35;phospholipase A2 inhibitory protein.
NCBI Gene Id16952
Protein NameAnnexin A1
Description of TargetPlays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity (PubMed:12475898). Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response (PubMed:12475898). Promotes resolution of inflammation and wound healing (PubMed:25664854). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells (PubMed:17948261). Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells (PubMed:17948261). Has no effect on unstimulated T-cells. Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration. Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton (By similarity). Has high affinity for Ca(2+) and can bind up to eight Ca(2+) ions (By similarity). Displays Ca(2+)-dependent binding to phospholipid membranes (By similarity). Plays a role in the formation of phagocytic cups and phagosomes (PubMed:21245195). Plays a role in phagocytosis by mediating the Ca(2+)-dependent interaction between phagosomes and the actin cytoskeleton (PubMed:21245195).
Uniprot IDP10107
Protein Accession #NP_034860.2
Nucleotide Accession #NM_010730
Molecular Weight39 kDa
  1. What is the species homology for "ANXA1 Antibody (OACD01660)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "ANXA1 Antibody (OACD01660)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery".

  3. What buffer format is "ANXA1 Antibody (OACD01660)" provided in?

    This item is provided in "Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ANXA1 Antibody (OACD01660)"?

    This target may also be called "annexin A1;annexin I;annexin-1;Anx;Anx-1;Anx-A1;C430014K04Rik;calpactin II;calpactin-2;chromobindin-9;lipocortin 1;lipocortin I;Lp;Lpc;Lpc1;Lpc-1;p35;phospholipase A2 inhibitory protein." in publications.

  5. What is the shipping cost for "ANXA1 Antibody (OACD01660)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ANXA1 Antibody (OACD01660)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ANXA1 Antibody (OACD01660)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "39 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ANXA1 Antibody (OACD01660)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Anxa1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Anxa1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Anxa1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Anxa1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Anxa1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Anxa1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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