Anti-uNOS Antibody (OAAI00226)

Catalog No: OAAI00226

Size:100UG

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
• Additional Information: Background: uNOS, macrophage NOS, belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS); induciblr NOS (iNOS) or macrophage NOS (mNOS); and endothelial NOS (eNOS). This antibody reacts with iNOS, bNOS and eNOS.
  Positive Control: Lung Tissue
  Cellular Location: Cytoplasmic
• Reconstitution and Storage: The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Immunogen: A synthetic peptide corrsponding to the internal segment of human uNos
• Purification: Affinity Purified
• Concentration: 100ug/200ul
• Specificity: NOS1/NOS2
• Formulation: This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Application Info: WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested

Target Info

• Gene Symbol: NOS1|NOS2
• Gene Full Name: nitric oxide synthase 1|nitric oxide synthase 2
• Alias Symbols: bNOS;constitutive NOS;hepatocyte NOS;HEP-NOS;IHPS1;inducible NO synthase;inducible NOS;INOS;NC-NOS;neuronal NOS;nitric oxide synthase 1 (neuronal);nitric oxide synthase 2, inducible;nitric oxide synthase 2A (inducible, hepatocytes);nitric oxide synthase, brain;nitric oxide synthase, inducible;nitric oxide synthase, macrophage;nNOS;N-NOS;NOS;NOS type I;NOS, type II;NOS2A;peptidyl-cysteine S-nitrosylase NOS1;peptidyl-cysteine S-nitrosylase NOS2.
• NCBI Gene Id: 4842|4843
• Description of Target: NOS catalyzes the oxidation of L-arginine to produce L-citrulline and NO. Nitric oxide (NO) is an organic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be enhanced through cellular responses to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. There are three types of NOS: two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II). This antibody recognizes all three types of NOS.
• Uniprot ID: P10600
• Molecular Weight: 150-160