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Datasheets/Manuals | Printable datasheet for Anti-TAFA2 Antibody (OAAI00405) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot |
Additional Information | Background: The TAFA2, also known as FAM19A2, is a secreted 12kDa protein. It belongs to the FAM19/TAFA family of chemokinelike. The family is composed of five highly homologous genes referred to as TAFA-1 to -5. The TAFA genes encode proteins of approximately 100 amino acids that contain conserved cysteine residues at fixed positions. TAFA-1 to -4 are more closely related to each other than to TAFA-5, in which a conserved motif including CC in TAFA-1 to -4 is not present. In H. sapiens, TAFA-3 has two isoforms formed by alternative splicing. TAFAs are highly expressed in central nervous system (CNS), and less extent in other tissues such as colon, heart, lung, spleen, kidney, and thymus. TAFA2 is expression is highest in the occipital and frontal cortex. TAFAs may modulate immune responses in the CNS by functioning as brainspecific chemokines, and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS. It may act as neurokines that regulates immune nervous cells . It may also control axonal sprouting following brain injury. |
:: | Positive Control: Brain tissue |
:: | Cellular Location: Extracellular or cytoplasmic |
Reconstitution and Storage | The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles. |
Immunogen | A synthetic peptide corresponding to the N-terminus of TAFA2 protein. This sequence is identical among human, mouse. |
Purification | Affinity Purified |
Concentration | 100ug/200ul |
Specificity | TAFA2 |
Formulation | This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer |
Application Info | WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested |
Reference | Tom Tang Y, Emtage P, Funk WD, Hu T, Arterburn M, Park EE, Rupp F. TAFA: a novel secreted family with conserved cysteine residues and restricted expression in the brain. Genomics. 2004 Apr;83(4):727-34. |
Gene Symbol | TAFA2 |
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Gene Full Name | TAFA chemokine like family member 2 |
Alias Symbols | chemokine-like protein TAFA-2;FAM19A2;family with sequence similarity 19 (chemokine (C-C motif)-like), member A2;family with sequence similarity 19 member A2, C-C motif chemokine like;protein FAM19A2;TAFA-2. |
NCBI Gene Id | 338811 |
Description of Target | The TAFA2, also known as FAM19A2, is a secreted 12kDa protein. It belongs to the FAM19/TAFA family of chemokinelike. The family is composed of five highly homologous genes referred to as TAFA-1 to -5. The TAFA genes encode proteins of approximately 100 amino acids that contain conserved cysteine residues at fixed positions. TAFA-1 to -4 are more closely related to each other than to TAFA-5, in which a conserved motif including CC in TAFA-1 to -4 is not present. In H. sapiens, TAFA-3 has two isoforms formed by alternative splicing. TAFAs are highly expressed in central nervous system (CNS), and less extent in other tissues such as colon, heart, lung, spleen, kidney, and thymus. TAFA2 is expression is highest in the occipital and frontal cortex. TAFAs may modulate immune responses in the CNS by functioning as brainspecific chemokines, and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS. It may act as neurokines that regulates immune nervous cells . It may also control axonal sprouting following brain injury. |
Uniprot ID | Q8N3H0 |
Molecular Weight | 12 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Anti-TAFA2 Antibody (OAAI00405)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "Anti-TAFA2 Antibody (OAAI00405)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "Anti-TAFA2 Antibody (OAAI00405)" provided in?
This item is provided in "Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Anti-TAFA2 Antibody (OAAI00405)"?
This target may also be called "chemokine-like protein TAFA-2;FAM19A2;family with sequence similarity 19 (chemokine (C-C motif)-like), member A2;family with sequence similarity 19 member A2, C-C motif chemokine like;protein FAM19A2;TAFA-2." in publications.
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What is the shipping cost for "Anti-TAFA2 Antibody (OAAI00405)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Anti-TAFA2 Antibody (OAAI00405)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Anti-TAFA2 Antibody (OAAI00405)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "12".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Anti-TAFA2 Antibody (OAAI00405)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "TAFA2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "TAFA2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "TAFA2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "TAFA2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "TAFA2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "TAFA2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.