Catalog No: OAPC00055
Size:100 ul
Price: $335.00
SKU
OAPC00055
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for OAPC00055
Product Info
Reference1. Terao E, Janssens S, van den Bosch de Aquilar P, Portier M, Klosen P (2000) In vivo
expression of the intermediate filament peripherin in rat motorneurons: modulation by
inhibitory and stimulatory signals. Neuroscience 101(3):679-88.
2.
Roberson J, Doroudchi MM, Nguyen MD, Durham, HD, Shaw G, Julien JP, Mushynski
WE. (2003) A neurotoxic peripherin splice variant in a mouse model of ALS. J. Cell Biol. 160(6):939-49.
3.
Boitard C, Villa MC, Becourt C, Gia HP, Huc C, Sempe P, Portier MM, Bach JF (1992)
Peripherin: an islet antigen that is cross-reactive with nonobese diabetic mouse class II gene products. Proc Natl Acad Sci USA 89(1):172-6.
Predicted Species ReactivityMost mammals
Product FormatLiquid.
ClonalityPolyclonal
HostChicken
ApplicationWB, IF
Additional InformationPackaging :
Liquid.
Reconstitution and StorageStore at -20C in undiluted aliquots; stable for at least 1 year. Avoid freeze/thaw cycles.
ImmunogenRecombinant rat peripherin expressed in and purified from E. coli.
PurificationTotal IgY fraction.
Predicted Homology Based on Immunogen SequenceMost mammals
SpecificitySpecific for the ~57kDa peripherin protein.
Application InfoThe antibody has been directly tested for reactivity in many mammalian tissues.
Immunostaining of cultured rat neurons and glia showing peripherin in green and alpha-internexin in red. Cells expressing both peripherin and alpha-internexin appear yellow.
Western blot of rat cerebellar lysate showing specific immunolabeling of the ~ 57k peripherin protein.
Gene SymbolPRPH
NCBI Gene Id3414
Protein NamePeripherin
Description of TargetPeripherin is a ~57kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. Subsequently, peripherin was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. In contrast to the neurofilaments, peripherin is strongly up-regulated after nerve injury (1). Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors (2). Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes (3). Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration.
Uniprot IDP21807
Molecular Weight~57kDa
  1. What is the species homology for "Anti-Peripherin (OAPC00055)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Most mammals".

  2. How long will it take to receive "Anti-Peripherin (OAPC00055)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "Anti-Peripherin (OAPC00055)" provided in?

    This item is provided in "Liquid.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Anti-Peripherin (OAPC00055)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "Anti-Peripherin (OAPC00055)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Anti-Peripherin (OAPC00055)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Anti-Peripherin (OAPC00055)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "~57kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Anti-Peripherin (OAPC00055)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PRPH"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PRPH"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PRPH"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PRPH"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PRPH"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PRPH"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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