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Datasheets/Manuals | Printable datasheet for Anti-HSP60 (Mab11-13) Antibody (OAED00191) (OAED00191) |
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Predicted Species Reactivity | Bovine|Dog|Dolphin|Drosophila|Fish|Guinea Pig|Hamster|Human|Monkey|Mosquito|Mouse|Porcine|Rabbit|Rat|Snake |
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Clonality | Monoclonal |
Clone | Mab-11-13 |
Isotype | IgG2a |
Host | Mouse |
Application | Flow cytometry|Immunofluorescence|Western blot |
Reconstitution and Storage | Long Term Storage : -20C |
Immunogen | Recombinant human Hsp60. |
Specificity | Recognizes human, mouse, rat, bovine, dog, dolphin, Drosophila, fish, guinea pig, hamster, mosquito, monkey, pig, rabbit and snake HSP60. Detects a band of ~60kDa by Western blot. |
Formulation | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
Purity | Protein G affinity purified. |
Application Info | Flow Cytometry (10μg/ml) Immunofluorescence Immunohistochemistry (paraffin sections) Western Blot (1:1000, colorimetric) Optimal conditions must be determined individually for each application. |
Gene Symbol | HSPD1 |
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Gene Full Name | heat shock protein family D (Hsp60) member 1 |
Alias Symbols | 60 kDa chaperonin;60 kDa heat shock protein, mitochondrial;chaperonin 60;CPN60;epididymis secretory sperm binding protein;GROEL;heat shock 60kDa protein 1 (chaperonin);Heat shock protein 60;heat shock protein 65;HLD4;HSP60;HSP-60;HSP65;HuCHA60;mitochondrial matrix protein P1;P60 lymphocyte protein;short heat shock protein 60 Hsp60s1;SPG13. |
NCBI Gene Id | 3329 |
Protein Name | 60 kDa heat shock protein, mitochondrial |
Description of Target | Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable). |
Uniprot ID | P10809 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Anti-HSP60 (Mab11-13) Antibody (OAED00191)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Dog|Dolphin|Drosophila|Fish|Guinea Pig|Hamster|Human|Monkey|Mosquito|Mouse|Porcine|Rabbit|Rat|Snake".
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How long will it take to receive "Anti-HSP60 (Mab11-13) Antibody (OAED00191)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 week".
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What buffer format is "Anti-HSP60 (Mab11-13) Antibody (OAED00191)" provided in?
This item is provided in "".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Anti-HSP60 (Mab11-13) Antibody (OAED00191)"?
This target may also be called "60 kDa chaperonin;60 kDa heat shock protein, mitochondrial;chaperonin 60;CPN60;epididymis secretory sperm binding protein;GROEL;heat shock 60kDa protein 1 (chaperonin);Heat shock protein 60;heat shock protein 65;HLD4;HSP60;HSP-60;HSP65;HuCHA60;mitochondrial matrix protein P1;P60 lymphocyte protein;short heat shock protein 60 Hsp60s1;SPG13." in publications.
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What is the shipping cost for "Anti-HSP60 (Mab11-13) Antibody (OAED00191)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Anti-HSP60 (Mab11-13) Antibody (OAED00191)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Anti-HSP60 (Mab11-13) Antibody (OAED00191)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Anti-HSP60 (Mab11-13) Antibody (OAED00191)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "HSPD1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "HSPD1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "HSPD1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "HSPD1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "HSPD1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "HSPD1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.