Catalog No: OAED00200
Size:50 ug
Price: $219.00
SKU
OAED00200
Availability: Domestic: within 1-2 week delivery | International: 1-2 week
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Datasheets/ManualsPrintable datasheet for Anti-Grp94 Antibody (OAED00200) (OAED00200)
Product Info
Predicted Species ReactivityBovine|Human|Mouse|Rat
ClonalityPolyclonal
HostRabbit
ApplicationImmunocytochemistry|Immunoprecipitation|Western blot
Reconstitution and StorageLong Term Storage : -20C
ImmunogenSynthetic peptide corresponding to the sequence near the C-terminus of mouse Grp94.
SpecificityRecognizes human, mouse, rat and bovine Grp94. Detects a band of ~94kDa by Western blot.
FormulationLiquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
PurityProtein A affinity purified.
Application InfoImmunocytochemistry
Immunohistochemistry (paraffin sections)
Immunoprecipitation (1:80)
Western Blot (1:1000)
Optimal conditions must be determined individually for each application.
ReferenceHeat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages: Z. Li, et al. ; Immunity 26, 215 (2007), Application(s): WB, IP using mouse & human cell lysates & tissue culture, Abstract;
Early intraneuronal Abeta deposition in the hippocampus of APP transgenic mice: L.W. Jin, et al. ; Neuroreport 14, 123 (2003), Application(s): ICC using mouse samples, Abstract;
Human U251MG glioma cells expressing the membrane form of macrophage colony-stimulating factor (mM-CSF) are killed by human monocytes in vitro and are rejected within immunodeficient mice via paraptosis that is associated with increased expression of three different heat shock proteins: M.R. Jadus, et al. ; Cancer Gene Ther. 10, 411 (2003), Application(s): IHC using human tissue, Abstract;
Induction of GRP78 by ischemic preconditioning reduces endoplasmic reticulum stress and prevents delayed neuronal cell death: P.H. Chan, et al. ; J. Cereb. Blood Flow Metab. 23, 949 (2003), Application(s): WB, IHC using rat samples, Abstract;
Overexpression of glucose-regulated protein94 (Grp94) in esophageal adenocarcinomas of a rat surgical model and humans: C.S. Yang, et al. ; Carcinogenesis 23, 123 (2002), Application(s): IHC, WB using rat & human samples, Abstract;
Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2: M. Mattson, et al. ; J. Neurochem. 79, 361 (2001), Application(s): WB using rat samples, Abstract;
The C-terminal domain of human grp94 protects the catalytic subunit of protein kinase CK2 (CK2 alpha) against thermal aggregation - role of disulfide bonds: E. Itarte, et al. ; Eur. J. Biochem. 268, 429 (2001), Application(s): WB using human samples, Abstract;
A novel human cytomegalovirus glycoprotein, gpUS9, which promotes cell-to-cell spread in polarized epithelial cells, colocalizes with the cytoskeletal proteins E-cadherin and F-actin: L. Pereira, et al. ; J. Virol. 72, 5717 (1998), Application(s): ICC using canine samples, Abstract;
Gene SymbolHsp90b1
Gene Full Nameheat shock protein 90, beta (Grp94), member 1
Alias Symbols94 kDa glucose-regulated protein;end;endoplasmic reticulum resident protein 99;endoplasmin;ERp;ERp99;gp9;gp96;GRP;GRP94;heat shock protein 90 kDa beta member 1;polymorphic tumor rejection antigen 1;TA-3;Tar;Targ2;Tr;Tra;Tra1;Tra-1;transforming growth factor alpha regulated gene 2;tumor rejection antigen (gp96) 1;tumor rejection antigen gp96.
NCBI Gene Id22027
Protein NameEndoplasmin
Description of TargetMolecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity).
Uniprot IDP08113
  1. What is the species homology for "Anti-Grp94 Antibody (OAED00200)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Human|Mouse|Rat".

  2. How long will it take to receive "Anti-Grp94 Antibody (OAED00200)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 week".

  3. What buffer format is "Anti-Grp94 Antibody (OAED00200)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Anti-Grp94 Antibody (OAED00200)"?

    This target may also be called "94 kDa glucose-regulated protein;end;endoplasmic reticulum resident protein 99;endoplasmin;ERp;ERp99;gp9;gp96;GRP;GRP94;heat shock protein 90 kDa beta member 1;polymorphic tumor rejection antigen 1;TA-3;Tar;Targ2;Tr;Tra;Tra1;Tra-1;transforming growth factor alpha regulated gene 2;tumor rejection antigen (gp96) 1;tumor rejection antigen gp96." in publications.

  5. What is the shipping cost for "Anti-Grp94 Antibody (OAED00200)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Anti-Grp94 Antibody (OAED00200)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Anti-Grp94 Antibody (OAED00200)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Anti-Grp94 Antibody (OAED00200)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Hsp90b1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Hsp90b1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Hsp90b1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Hsp90b1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Hsp90b1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Hsp90b1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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