Catalog No: OAAI00607
Size:100UG
Price: $329.00
SKU
OAAI00607
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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Datasheets/ManualsPrintable datasheet for Anti-FOXA3/HNF3G Polyclonal Antibody (OAAI00607)
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid PBS (pH 7.2) containing antibody stabilizer
ClonalityPolyclonal
IsotypeRabbit IgG
HostRabbit
ApplicationEnzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
Additional InformationPositive Control: HepG2 cells
Cellular Location: Nucleus.
Reconstitution and StorageThe antibodies are stable for 24 months from date of receipt when stored at -20°C to -70°C. The antibodies can be stored at 2-8°C for three months without detectable loss of activity. Avoid repeated freezing-thawing cycles.
ImmunogenA synthetic peptide corresponding to the C-terminus of human FOXA3 protein. This sequence is identical to rat, mouse and human origins.
PurificationEpitope Affinity Purification
Concentration0.5 mg/ml
SpecificityThis antibody recognizes ~37 kDa of FOXA3 protein.
Application InfoWB: 0.1-1 ug/mL
ELISA: 0.01-1 ug/mL
IP: 2-5 ug/mL
IHC: 2-10 ug/mL
ReferenceShen W et al. Foxa3 (hepatocyte nuclear factor 3gamma ) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast. 2001 Nov 16;276(46):42812-7.
Gene SymbolFOXA3
Gene Full Nameforkhead box A3
Alias SymbolsFKHH3;fork head-related protein FKH H3;forkhead box protein A3;hepatocyte nuclear factor 3-gamma;HNF3G;HNF-3G;HNF-3-gamma;TCF3G;TCF-3G;transcription factor 3G.
NCBI Gene Id3171
Description of TargetThe forkhead box gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA1 plays an important role in breast cancer. The FOXA subfamily is composed of the transcription factors FOXA1, A2, A3. They were discovered as the regulators of hepatic genes. Foxa1 has been shown to be required for glucagon secretion in the pancreas, whereas Foxa2 is critical for the regulation of insulin secretion in pancreatic beta-cells.
Foxa3 is important in the maintenance of glucose homeostasis, it is the dominating transcriptional regulator of GLUT2 expression in hepatocytes in vivo. In the normal activation of HNF-4alpha, HNF-1alpha, and PGC-1 induced by fasting is attenuated in mice lacking Foxa3.
Uniprot IDP55318
Molecular Weight48 kDa
  1. What is the species homology for "Anti-FOXA3/HNF3G Polyclonal Antibody (OAAI00607)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "Anti-FOXA3/HNF3G Polyclonal Antibody (OAAI00607)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "Anti-FOXA3/HNF3G Polyclonal Antibody (OAAI00607)" provided in?

    This item is provided in "Liquid PBS (pH 7.2) containing antibody stabilizer".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Anti-FOXA3/HNF3G Polyclonal Antibody (OAAI00607)"?

    This target may also be called "FKHH3;fork head-related protein FKH H3;forkhead box protein A3;hepatocyte nuclear factor 3-gamma;HNF3G;HNF-3G;HNF-3-gamma;TCF3G;TCF-3G;transcription factor 3G." in publications.

  5. What is the shipping cost for "Anti-FOXA3/HNF3G Polyclonal Antibody (OAAI00607)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Anti-FOXA3/HNF3G Polyclonal Antibody (OAAI00607)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Anti-FOXA3/HNF3G Polyclonal Antibody (OAAI00607)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "48 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Anti-FOXA3/HNF3G Polyclonal Antibody (OAAI00607)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "FOXA3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "FOXA3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "FOXA3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "FOXA3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "FOXA3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "FOXA3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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