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Anti-ERK2 Antibody (CT) Polyclonal Antibody (OAAI00228)

100 ug
$360.00
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Gene Symbol:
CLDN4
Official Gene Full Name:
claudin 4
NCBI Gene Id:
1364
Swissprot Id:
O14493
Alias Symbols:
CPER, CPE-R, CPETR, CPETR1, WBSCR8, hCPE-R,
Replacement Item:
This antibody may replace item sc-28666 from Santa Cruz Biotechnology.
Description of Target:
The extracellular signal-regulated kinases ½ (ERK1/2) are known as MAPK (Mitogen-activated protein kinases) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell prolifeRation, differentiation, motility, and death. ERK2 is also known as mitogen activated protein kinase 2, microtubule-associated protein-2 kinase, MAP kinse 2, p42-MAPK or EGF receptor T669 (ERT1). The p44/42 MAPK (ERK1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer. The phosphorylation of MAPK at Thr202 and Tyr 204 are correlated to the progression and metastatic potential of tumor cells.
Molecular Weight:
42 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The Rabbit IgG is purified by Epitope Affinity Purification.
Application:
IHC, WB, IP
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CLDN4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CLDN4.
Immunogen:
A synthetic peptide derived from C-terminus of ERK2 protein from Human, Rat, Mouse and dog origins.
Predicted Species Reactivity:
Human, Mouse, Rat
Reconstitution and Storage:
The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity.
Avoid repeated freezing thawing cycles.
Datasheets/Manuals:
Printable datasheet for Rabbit Anti-ERK2 Antibody (CT) Polyclonal Antibody OAAI00228
Specificity:
This antibody recognizes ERK2. It reacts with Human, Rat, Mouse species. The other species are not tested.
Isotype:
Rabbit IgG
Application Info:
Positive Control: A431 Cell Lysate
Western Blot: 0.1-1 μg/ml
ELISA: 0.01-0.1 μg/ml
IP: 2-5 μg/ml
IHC: 1:200
Target Reference:
M. Klink, et al. Ovarian Cancer Cells Modulate Human Blood Neutrophils Response to Activation In Vitro. Clinical Immunology, 68 (3), 328-336. 2008.

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