Size:100 ug
$360.00
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SKU
OAAI00284
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Anti-EGFR Monoclonal Antibody (OAAI00284)

Catalog#: OAAI00284
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human, Mouse, Rat
Clonality Monoclonal
Isotype Mouse IgG1
Host Mouse
Application WB, IP, IHC
Reconstitution and Storage The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity.
Avoid repeated freezing thawing cycles.
Replacement Item This antibody may replace item sc-03, HPA001200, HPA018530
Immunogen An Extracellular domain of Human recombinant EGFR protein as an immunogen
Purification The Mouse IgG is purified by Isotyping-specific Affinity Purification.
Datasheets/Manuals Printable datasheet for Mouse Anti-EGFR Monoclonal Antibody OAAI00284
Specificity This antibody recognizes EGFR protein. It cross-reacts with Human, Rat and Mouse. The other species was not tested.
Application Info Positive Control: Placenta, A431
Western Blot: 0.1-1 μg/ml
ELISA: 0.01-0.1 μg/ml
IP: 2-5 μg/ml
IHC: 2-5 μg/ml
Target Reference Davis,R.J. and Czech,M.P. Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal Human fibroblasts at threonine-654. Proc. Natl. Acad. Sci. U.S.A. 82 (7), 1974-1978 (1985)
Gene Symbol EGFR
Official Gene Full Name epidermal growth factor receptor
Alias Symbols ERBB, HER1, mENA, ERBB1, PIG61,
NCBI Gene Id 1956
Description of Target EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Swissprot Id P00533
Molecular Weight ~170 kDa (WT), 145 (VIII Variant)
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express EGFR.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express EGFR.
  1. What is the species homology for "Anti-EGFR Monoclonal Antibody (OAAI00284)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "Anti-EGFR Monoclonal Antibody (OAAI00284)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "Anti-EGFR Monoclonal Antibody (OAAI00284)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Anti-EGFR Monoclonal Antibody (OAAI00284)"?

    This target may also be called "ERBB, HER1, mENA, ERBB1, PIG61, " in publications.

  5. What is the shipping cost for "Anti-EGFR Monoclonal Antibody (OAAI00284)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Anti-EGFR Monoclonal Antibody (OAAI00284)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Anti-EGFR Monoclonal Antibody (OAAI00284)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "~170 kDa (WT), 145 (VIII Variant)".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Anti-EGFR Monoclonal Antibody (OAAI00284)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "EGFR"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "EGFR"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "EGFR"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "EGFR"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "EGFR"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "EGFR"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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