Anti-dNK Polyclonal Antibody (OAAI00510)

Catalog No: OAAI00510

Size:100UG

WB: The tissue extract derived from fruit fly was immunoblotted by Rabbit anti dNK (Cat#OAAI00510) at 1:500. An immunoreactive band is observed ~30 kDa.

Product Info

• Predicted Species Reactivity: Fruit fly
• Product Format: Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
• Additional Information: Background: Deoxynucleoside kinases (dNK) are key enzymes in deoxyribonucleoside salvage, activating several clinically important chemotherapeutic drugs. Deoxynulceoside kinases catalyze the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribocytidine kinase (dCK), deoxyriboguanosine kinase(dGK), cytosolic thymidine kinase(TK1) and mitochondrial thymidine kinase (TK2).
  Positive Control: Fruit-fly extract
• Reconstitution and Storage: The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Immunogen: A synthetic peptide corresponding to the N-terminus of fruit fly Deoxynucleoside kinase protein.
• Purification: Affinity Purified
• Concentration: 100ug/200ul
• Formulation: This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Application Info: WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested
• Reference: Hoskins,R.A., et al. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Science 316 (5831), 1625-1628 (2007) Sraffan Eriksson et al., Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy. Advances in Enzyme Regulation 34, pp13-25 (1994).
  

Target Info

• Gene Symbol: dnk
• Gene Full Name: deoxyribonucleoside kinase
• Alias Symbols: DNK, 2'-deoxynucleoside kinase, DM-dNK
• Description of Target: Deoxynucleoside kinases (dNK) are key enzymes in deoxyribonucleoside salvage, activating several clinically important chemotherapeutic drμgs. Deoxynulceoside kinases catalyze the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribocytidine kinase (dCK), deoxyriboguanosine kinase(dGK), cytosolic thymidine kinase(TK1) and mitochondrial thymidine kinase (TK2).
  
• Molecular Weight: 30