Anti-Collagen Type I Antibody (OARA02578)

Catalog No: OARA02578 (Formerly GWB-E84DBC)

Size:100UG

Product Info

• Predicted Species Reactivity: Bovine|Human|Mammal|Mouse|Porcine|Rat
• Product Format: Liquid (sterile filtered)
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Dot blot|Enzyme-linked immunosorbent assay|Flow cytometry|Fluorescence-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunoprecipitation|Multiplex assay|Western blot
• Reconstitution and Storage: 2°C to 8°C|-20°C
• Immunogen: Collagen Type I from human and bovine placenta
• Purification: COLLAGEN I Antibody has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other collagens, human serum proteins and non-collagen extracellular matrix proteins to remove any unwanted specificities.
• Concentration: 1.00 mg/ml
• Specificity: Typically negligible cross reactivity against other types of collagens was detected by ELISA against purified standards. Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues. This antibody reacts with most mammalian Type I collagens and has negligible cross-reactivity with Type II, III, IV, V or VI collagens. Non-specific cross-reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins is negligible.
• Application Info: Anti-Collagen antibodies have been used for indirect trapping ELISA for quantitation of antigen in serum using a standard curve, immunoprecipitation, native (non-denaturing, non-dissociating) PAGE, immunohistochemistry, Immunofluorescence, FLOW, and western blotting for highly sensitive qualitative analysis.
• Application Data: ELISA: 1:5000~50000
  FLISA: 1:100
  IHC: 1:50~200
  IP: 1:100

Target Info

• Gene Symbol: COL1A1
• Gene Full Name: collagen type I alpha 1 chain
• Alias Symbols: alpha-1 type I collagen;alpha1(I) procollagen;CAFYD;collagen alpha 1 chain type I;collagen alpha-1(I) chain;collagen alpha-1(I) chain preproprotein;collagen of skin, tendon and bone, alpha-1 chain;collagen, type I, alpha 1;EDSARTH1;EDSC;OI1;OI2;OI3;OI4;pro-alpha-1 collagen type 1;type I proalpha 1;type I procollagen alpha 1 chain.
• NCBI Gene Id: 1277
• Protein Name: Collagen alpha-1(I) chain|collagen alpha-1(I) chain preproprotein [Homo sapiens]
• Description of Target: Type I collagen is a member of group I collagen (fibrillar forming collagen).
• Uniprot ID: P02452
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_000079.2