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Datasheets/Manuals | Printable datasheet for Anti-BCMA (human) (Vicky-1) Antibody (OAED00318) (OAED00318) |
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Predicted Species Reactivity | Human |
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Clonality | Monoclonal |
Clone | Vicky-1 |
Isotype | IgG1 |
Host | Rat |
Application | Enzyme-linked immunosorbent assay|Flow cytometry|Functional assay|Immunocytochemistry|Western blot |
Reconstitution and Storage | Long Term Storage : -20C Short Term Storage : -20C Handling : Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored as recommended. |
Immunogen | Recombinant human BCMA extracellular domain (aa 2-54) (Prod. No. ALX-522-026). |
Concentration | 1mg/ml |
Specificity | Recognizes human BCMA. Does not cross-react with mouse BCMA. |
Formulation | Liquid. In PBS containing 0.02% sodium azide. |
Purity | Protein G-affinity purified. |
Application Info | ELISA Flow Cytometry Immunocytochemistry Functional Application (blocks binding of BAFF to human BCMA) Optimal conditions must be determined individually for each application. |
Reference | Autoantibody-producing RP105(-) B cells, from patients with systemic lupus erythematosus, showed more preferential expression of BCMA compared with BAFF-R than normal subjects: S. Koarada, et al.; Rheumatology (Oxford) 49, 662 (2010), Abstract; Full Text The rGel/BLyS fusion toxin inhibits diffuse large B-cell lymphoma growth in vitro and in vivo: M.A. Lyu, et al.; Neoplasia 12, 366 (2010), Abstract; TACI regulates IgA production by APRIL in collaboration with HSPG: D. Sakurai, et al.; Blood 109, 2961 (2007), Abstract; BAFF AND APRIL: a tutorial on B cell survival: F. Mackay, et al.; Annu. Rev. Immunol. 21, 231 (2003), Abstract; BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population: J.S. Thompson, et al.; J. Exp. Med. 192, 129 (2000), Abstract; Full Text |
Gene Symbol | TNFRSF17 |
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Gene Full Name | TNF receptor superfamily member 17 |
Alias Symbols | B cell maturation antigen;B-cell maturation factor;B-cell maturation protein;BCM;BCMA;CD269;TNFRSF13A;tumor necrosis factor receptor superfamily member 17. |
NCBI Gene Id | 608 |
Protein Name | Tumor necrosis factor receptor superfamily member 17 |
Description of Target | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
Uniprot ID | Q02223 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Anti-BCMA (human) (Vicky-1) Antibody (OAED00318)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "Anti-BCMA (human) (Vicky-1) Antibody (OAED00318)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 week".
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What buffer format is "Anti-BCMA (human) (Vicky-1) Antibody (OAED00318)" provided in?
This item is provided in "".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Anti-BCMA (human) (Vicky-1) Antibody (OAED00318)"?
This target may also be called "B cell maturation antigen;B-cell maturation factor;B-cell maturation protein;BCM;BCMA;CD269;TNFRSF13A;tumor necrosis factor receptor superfamily member 17." in publications.
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What is the shipping cost for "Anti-BCMA (human) (Vicky-1) Antibody (OAED00318)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Anti-BCMA (human) (Vicky-1) Antibody (OAED00318)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Anti-BCMA (human) (Vicky-1) Antibody (OAED00318)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Anti-BCMA (human) (Vicky-1) Antibody (OAED00318)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "TNFRSF17"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "TNFRSF17"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "TNFRSF17"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "TNFRSF17"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "TNFRSF17"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "TNFRSF17"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.