Anti-BAFF-R (human) (11C1) Antibody (OAED00346)

Catalog No: OAED00346

Size:100 ug

Figure 1: Detection of endogenous BAFF-R in a human palatine tonsil paraffin section stained with the MAb to BAFF-R (human) (11C1). An intense staining of B cells follicles and weaker staining of germinal center is observed (200x).

Product Info

• Predicted Species Reactivity: Human
• Clonality: Monoclonal
• Clone: 11C1
• Isotype: IgG1
• Host: Mouse
• Application: FC, IHC
• Reconstitution and Storage: Long Term Storage : +4C
  Short Term Storage : +4C
  Handling : Avoid freeze/thaw cycles.
  For long-term storage, aliquot and freeze at -20C.
  Stable for at least 6 months after receipt when stored as recommended.
• Immunogen: Mouse B cell lymphoma L1.2 cells expressing human BAFF-R.
• Concentration: 1mg/ml
• Specificity: Recognizes human BAFF-R.
• Source: Purified from concentrated mouse hybridoma tissue culture supernatant.
• Formulation: Liquid. In PBS containing 0.02% sodium azide.
• Purity: Protein G-affinity purified.
  ≥95% (SDS-PAGE)
• Application Info: Flow Cytometry: works on endogenous.
  Immunohistochemistry (frozen sections; paraffin sections): works on endogenous.
• Reference: Autoantibody-producing RP105(-) B cells, from patients with systemic lupus erythematosus, showed more preferential expression of BCMA compared with BAFF-R than normal subjects: S. Koarada, et al.; Rheumatology (Oxford) 49, 662 (2010), Abstract; Full Text
  B cell-activating factor belonging to the TNF family (BAFF)-R Is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells: L.G. Ng, et al.; J. Immunol. 173, 807 (2004), Abstract;
  

Target Info

• Gene Symbol: TNFRSF13C
• Alias Symbols: BAFFR, CD268, CVID4, BAFF-R, BROMIX, prolixin
• NCBI Gene Id: 115650
• Protein Name: Tumor necrosis factor receptor superfamily member 13C
• Uniprot ID: Q96RJ3