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Datasheets/Manuals | Printable datasheet for OAPC00130 |
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Predicted Species Reactivity | Human, Mouse, Rat |
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Product Format | Liquid. 100 ul in PBS |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB, IF |
Additional Information | Packaging : 100 ul in PBS |
Reconstitution and Storage | Store at -20C in undiluted aliquots; stable for at least 1 year. Avoid freeze/thaw cycles. |
Immunogen | Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat adenylate cyclase III conjugated to KLH. |
Purification | Affinity purified rabbit serum. |
Predicted Homology Based on Immunogen Sequence | Human; Mouse; Rat |
Specificity | Specific for the ~160 kDa adenylate cyclase III protein. |
Application Info | The antibody has been directly tested for reactivity in human, mouse and rat. Western blot of rat cortex lysate showing specific immunolabeling of the ~160k adenylate cyclase III protein. Immunofluorescence of cultured rat neurons and glia showing strong staining of neuronal cilia using our anti-adenylate cyclase III antibody (red) and axonal and dendritic staining of alpha II spectrin (cat. # OAPC00143) (green) revealing the submembraneous cytoskeleton and DNA (blue). |
Reference | Fuchs JL, Schwark HD. (2004) Neuronal primary cilia: a review. Cell Biol Int. 28:111-8. Louvi A and Grove EA. (2011) Cilia in the CNS: the quiet organelle claims center stage. Neuron 69:1046-1060 |
Gene Symbol | ADCY3 |
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NCBI Gene Id | 64508 |
Protein Name | Adenylate cyclase type 3 |
Description of Target | Adenylate cyclase is the enzyme which produces the "second messenger" signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004; Louvi and Grove 2011). |
Uniprot ID | P21932 |
Protein Accession # | NP_570135.2 |
Molecular Weight | ~160 - 200 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Anti-Adenylate Cyclase III (OAPC00130)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "Anti-Adenylate Cyclase III (OAPC00130)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "Anti-Adenylate Cyclase III (OAPC00130)" provided in?
This item is provided in "Liquid. 100 ul in PBS".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Anti-Adenylate Cyclase III (OAPC00130)"?
This target may also be called "" in publications.
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What is the shipping cost for "Anti-Adenylate Cyclase III (OAPC00130)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Anti-Adenylate Cyclase III (OAPC00130)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Anti-Adenylate Cyclase III (OAPC00130)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "~160 - 200 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Anti-Adenylate Cyclase III (OAPC00130)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ADCY3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ADCY3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ADCY3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ADCY3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ADCY3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ADCY3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.