Catalog No: OAAB15620
Size:400ul
Price: $450.00
SKU
OAAB15620
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAAB15620
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid. PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWB, E
Additional InformationFunction: Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes.
Cellular Location: Cell membrane; Multi-pass membrane protein Note=Shows an intracellular localization
Tissue Location: Expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer
Reconstitution and StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis ANO6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human ANO6.
PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration0.3 mg/ml
SpecificityThis ANO6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human ANO6.
Intended UseFor research use only and not for use in diagnostic or therapeutic procedures.
Application InfoWB: 1:1,000
Optimal dilutions should be determined by the end user.
ReferenceRose, J. Phd, et al. Mol. Med. (2010) In press
Hartzell, H.C., et al. J. Physiol. (Lond.) 587 (PT 10), 2127-2139 (2009)
Katoh, M., et al. Int. J. Oncol. 24(5):1345-1349(2004)
Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995)
Gene SymbolANO6
Alias SymbolsSCTS, BDPLT7, TMEM16F
NCBI Gene Id196527
Protein NameAnoctamin-6
Description of TargetMay act as a calcium-activated chloride channel.
Uniprot IDQ4KMQ2
Protein Accession #NP_001020527.2
Molecular Weight106 kDa
  1. What is the species homology for "ANO6 Antibody - N-terminal region (OAAB15620)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "ANO6 Antibody - N-terminal region (OAAB15620)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "ANO6 Antibody - N-terminal region (OAAB15620)" provided in?

    This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ANO6 Antibody - N-terminal region (OAAB15620)"?

    This target may also be called "SCTS, BDPLT7, TMEM16F" in publications.

  5. What is the shipping cost for "ANO6 Antibody - N-terminal region (OAAB15620)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ANO6 Antibody - N-terminal region (OAAB15620)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ANO6 Antibody - N-terminal region (OAAB15620)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "106 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ANO6 Antibody - N-terminal region (OAAB15620)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ANO6"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ANO6"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ANO6"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ANO6"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ANO6"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ANO6"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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