Catalog No: OPCD01336
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OPCD01336
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Datasheets/ManualsPrintable datasheet for ANO1 Recombinant Protein (OPCD01336)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ser20-Val239
::Subcellular Location: Cell membrane; Multi-pass membrane protein. Cytoplas
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolAno1
Gene Full Nameanoctamin 1, calcium activated chloride channel
Alias Symbolsanoctamin-1;Tmem16;Tmem16a;transmembrane protein 16A.
NCBI Gene Id101772
Protein NameAnoctamin-1
Description of TargetCalcium-activated chloride channel (CaCC) which plays an important role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Uniprot IDQ8BHY3
Protein Accession #NP_001229278.1
Nucleotide Accession #NM_001242349.1
Protein Size (# AA)Ser20~Val239
Molecular Weight38kDa
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