Size:400ul
$329.00
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SKU
OAAB06341
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ANKH Antibody - C-terminal region (OAAB06341)

Catalog#: OAAB06341
Domestic: within 1 week delivery | International: 1 week
More Information
Tested Species Reactivity Human, Rat
Predicted Species Reactivity Rat
Product Format Liquid. PBS with 0.09% (W/V) sodium azide.
Clonality Polyclonal
Isotype Rabbit Ig
Host Rabbit
Application WB, IHC-P, FC, ELISA
Additional Information Cellular Location: Membrane; Multi-pass membrane protein
Tissue Location: Found in osteoblasts from mandibular bone and from iliac bone; not detected in osteoclastic cells.
Reconstitution and Storage Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-67242 from Santa Cruz Biotechnology.
Immunogen This ANKH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-492 amino acids from the C-terminal region of human ANKH.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration 0.5 mg/ml
Datasheets/Manuals Printable datasheet for anti-ANKH antibody - OAAB06341
Intended Use For research use only and not for use in diagnostic or therapeutic procedures.
Application Info WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50
Optimal dilutions should be determined by the end user.
Other Applications Image 1 Data ANKH Antibody (C-term) flow cytometric analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Publications

Szeri, et al. The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP. PLoS Genetics 2020 Jul 8;16(7):e1008884. WB, IHC-P, FC, ELISA, Rat 32639996

Gene Symbol ANKH
Alias Symbols Progressive ankylosis protein homolog, ANK, ANKH, KIAA1581
NCBI Gene Id 56172
Protein Name Progressive ankylosis protein homolog
Description of Target ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.
Swissprot Id Q9HCJ1
Protein Accession # NP_473368.1
Molecular Weight 54 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ANKH.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ANKH.
  1. What is the species homology for "ANKH Antibody - C-terminal region (OAAB06341)"?

    The tested species reactivity for this item is "Human, Rat". This antibody is predicted to have homology to "Rat".

  2. How long will it take to receive "ANKH Antibody - C-terminal region (OAAB06341)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "ANKH Antibody - C-terminal region (OAAB06341)" provided in?

    This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ANKH Antibody - C-terminal region (OAAB06341)"?

    This target may also be called "Progressive ankylosis protein homolog, ANK, ANKH, KIAA1581" in publications.

  5. What is the shipping cost for "ANKH Antibody - C-terminal region (OAAB06341)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ANKH Antibody - C-terminal region (OAAB06341)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ANKH Antibody - C-terminal region (OAAB06341)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "54 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ANKH Antibody - C-terminal region (OAAB06341)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "ANKH"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ANKH"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ANKH"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ANKH"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ANKH"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ANKH"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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