ANGPTL2 Antibody - N-terminal region (ARP54835_P050)

Catalog No: ARP54835_P050

WB Suggested Anti-ANGPTL2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: 721_B cell lysateThere is BioGPS gene expression data showing that ANGPTL2 is expressed in 721_B

Host: Rabbit
Target Name: GNAS
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: SLC13A3
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANGPTL2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: NSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEVK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ANGPTL2 (ARP54835_P050) antibody is Catalog # AAP54835 (Previous Catalog # AAPP31639)
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that ANGPTL2 is expressed in 721_B

• Reference: Sun,H., Nephron Exp. Nephrol. 105 (4), E117-E123 (2007)
• Publications:

  Doblinger, E. et al. Angiotensin AT1 receptor-associated protein Arap1 in the kidney vasculature is suppressed by angiotensin II. Am. J. Physiol. Renal Physiol. 302, F1313-24 (2012). 22357923

Target Info

• Gene Symbol: ANGPTL2
• Gene Full Name: Angiopoietin-like 2
• Alias Symbols: ARP2, HARP
• NCBI Gene Id: 23452
• Protein Name: Angiopoietin-related protein 2
• Description of Target: Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-127 AL598400.1 2-128 128-451 AL598400.1 129-452 452-2289 BC012368.1 325-2162 2290-3572 AK074726.1 1294-2576
• Uniprot ID: Q9UKU9
• Protein Accession #: NP_036230
• Nucleotide Accession #: NM_012098
• Protein Size (# AA): 493
• Molecular Weight: 57kDa