Catalog No: ARP34661_P050
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ARP34661_P050
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Datasheets/ManualsPrintable datasheet for anti-AMOT (ARP34661_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human AMOT
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: TANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNE
Concentration0.5 mg/ml
Blocking PeptideFor anti-AMOT (ARP34661_P050) antibody is Catalog # AAP34661 (Previous Catalog # AAPP23628)
Sample Type Confirmation

AMOT is supported by BioGPS gene expression data to be expressed in HEK293T

ReferenceHolmgren,L., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (24), 9208-9213
Publications

Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice. PLoS Biol. 17, e3000253 (2019). 31042703

Gene SymbolAMOT
Gene Full NameAngiomotin
Alias SymbolsKIAA1071
NCBI Gene Id154796
Protein NameAngiomotin
Description of TargetAMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
Uniprot IDQ4VCS5
Protein Accession #NP_573572
Nucleotide Accession #NM_133265
Protein Size (# AA)675
Molecular Weight72kDa
Protein InteractionsAMOT; C1orf216; WDYHV1; MED4; SNAPC5; PPP2R4; LURAP1; UNC119; LMO4; PIN1; MAGEA4; KRT31; KRT15; FUS; SEPT1; CEP76; HAUS2; LATS2; CEP250; CDKN1A; ACTB; ACTA1; YAP1; SART3; AURKB; MAPK3; BAG3; WWOX; ITCH; LATS1; YWHAG; UBC; PARK2; AMOTL1; SPICE1; MPP7; CNTR
  1. What is the species homology for "AMOT Antibody - N-terminal region (ARP34661_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "AMOT Antibody - N-terminal region (ARP34661_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "AMOT Antibody - N-terminal region (ARP34661_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "AMOT Antibody - N-terminal region (ARP34661_P050)"?

    This target may also be called "KIAA1071" in publications.

  5. What is the shipping cost for "AMOT Antibody - N-terminal region (ARP34661_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "AMOT Antibody - N-terminal region (ARP34661_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "AMOT Antibody - N-terminal region (ARP34661_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "72kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "AMOT Antibody - N-terminal region (ARP34661_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "AMOT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "AMOT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "AMOT"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "AMOT"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "AMOT"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "AMOT"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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