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| Datasheets/Manuals | Printable datasheet for anti-ALS2 antibody - OAAB03484 |
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| Predicted Species Reactivity | Human, Mouse |
|---|---|
| Product Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Host | Rabbit |
| Application | WB, IHC |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This ALS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2. |
| Predicted Homology Based on Immunogen Sequence | Human; Mouse |
| Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Application Info | WB: 1:1000 IHC-P: 1:50~100 |
| Gene Symbol | ALS2 |
|---|---|
| Alias Symbols | ALSJ, PLSJ, IAHSP, ALS2CR6 |
| NCBI Gene Id | 57679 |
| Protein Name | Alsin |
| Description of Target | ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. |
| Uniprot ID | Q96Q42 |
| Protein Accession # | NP_001129217.1 |
| Molecular Weight | 183666 Da |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ALS2 Antibody - C-terminal region (OAAB03484)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".
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How long will it take to receive "ALS2 Antibody - C-terminal region (OAAB03484)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "ALS2 Antibody - C-terminal region (OAAB03484)" provided in?
This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ALS2 Antibody - C-terminal region (OAAB03484)"?
This target may also be called "ALSJ, PLSJ, IAHSP, ALS2CR6" in publications.
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What is the shipping cost for "ALS2 Antibody - C-terminal region (OAAB03484)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ALS2 Antibody - C-terminal region (OAAB03484)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ALS2 Antibody - C-terminal region (OAAB03484)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "183666 Da".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ALS2 Antibody - C-terminal region (OAAB03484)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ALS2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ALS2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ALS2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ALS2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ALS2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ALS2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
