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ALOXE3 Antibody (OAGA00572)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IHC-FFPE, WB
Additional Information:
Background: The leukotrienes constitute a group of arachidonic acid-derived compounds with biologic activities suggesting important roles in inflammation and immediate hypersensitivity. These compounds are catabolized, in part, by lipoxygenases. Epidermis-type lipoxygenases, a distinct subclass within the multigene family of mammalian lipoxygenases, are novel isoenzymes isolated from human and mouse skin including human ALOX15B (MIM 603697), human and mouse ALOX12B (MIM 603741), mouse 8S-LOX, and mouse e-LOX-3.[supplied by OMIM]
:::
Positive Controls: HepG2
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item:
This antibody may replace item sc-133273 from Santa Cruz Biotechnology.
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 294 of ALOXE3 (Uniprot ID#Q9BYJ1)
Purification:
Purified by antigen-affinity chromatography.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-ALOXE3 antibody - OAGA00572
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol:
ALOXE3
Official Gene Full Name:
Epidermis-type lipoxygenase 3
Alias Symbols:
E-LOX antibody, MGC119694 antibody, MGC119695 antibody, MGC119696 antibody, eLOX3 antibody, ALOXE3 antibody, e-LOX-3 antibody, epidermal lipoxygenase antibody, epidermis-type lipoxygenase 3 antibody, arachidonate lipoxygenase 3 antibody
NCBI Gene Id:
59344
Protein Name:
Epidermis-type lipoxygenase 3
Swissprot Id:
Q9BYJ1
Protein Accession #:
NP_001159432.1
Molecular Weight:
81 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ALOXE3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ALOXE3.

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