Size:100 ul
Special Price $229.00 Regular Price $319.00
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ARP48974_P050
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Conjugation Options

ARP48974_P050-FITC Conjugated

ARP48974_P050-HRP Conjugated

ARP48974_P050-Biotin Conjugated

ALG2 Antibody - C-terminal region (ARP48974_P050)

Catalog#: ARP48974_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-107140 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ALG2
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 93%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 93%
Complete computational species homology data Anti-ALG2 (ARP48974_P050)
Peptide Sequence Synthetic peptide located within the following region: QSDLGQYVTFLRSFSDKQKISLLHSCTCVLYTPSNEHFGIVPLEAMYMQC
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-ALG2 (ARP48974_P050) antibody is Catalog # AAP48974 (Previous Catalog # AAPY02114)
Datasheets/Manuals Printable datasheet for anti-ALG2 (ARP48974_P050) antibody
Target Reference Draeby,I., (2007) Arch. Biochem. Biophys. 467 (1), 87-94
Publications

Cossins, J. et al. Congenital myasthenic syndromes due to mutations in ALG2 and ALG14. Brain 136, 944-56 (2013). WB, Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish 23404334

Rind, N. et al. A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip. Hum. Mol. Genet. 19, 1413-24 (2010). WB, Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish 20080937

Gene Symbol ALG2
Official Gene Full Name Asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae)
Alias Symbols CDGIi, FLJ14511, hALPG2, NET38
NCBI Gene Id 85365
Protein Name Alpha-1,3/1,6-mannosyltransferase ALG2
Description of Target ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot Id Q9H553
Protein Accession # NP_149078
Nucleotide Accession # NM_033087
Protein Size (# AA) 416
Molecular Weight 47kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ALG2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ALG2.
Protein Interactions UBC; PLSCR3; SHISA5; PDCD6IP; ALG2; VPS28; PTPN23; SEC31A; TSG101; LAMP1; HSP90AA1; PTK2B; ANXA11; ANXA7; VPS37A; PEF1; SRI;
  1. What is the species homology for "ALG2 Antibody - C-terminal region (ARP48974_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish".

  2. How long will it take to receive "ALG2 Antibody - C-terminal region (ARP48974_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ALG2 Antibody - C-terminal region (ARP48974_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ALG2 Antibody - C-terminal region (ARP48974_P050)"?

    This target may also be called "CDGIi, FLJ14511, hALPG2, NET38" in publications.

  5. What is the shipping cost for "ALG2 Antibody - C-terminal region (ARP48974_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ALG2 Antibody - C-terminal region (ARP48974_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ALG2 Antibody - C-terminal region (ARP48974_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "47kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ALG2 Antibody - C-terminal region (ARP48974_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "ALG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ALG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ALG2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ALG2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ALG2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ALG2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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