ALDOA Protein (OPPA02049)

Catalog No: OPPA02049 (Formerly GWB-791DD1)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: The ALDOA solution contains 20mM Tris-HCl pH-8, 0.1M NaCl and 20% glycerol. Physical appearance: Sterile Filtered clear colorless solution.
• Host: E. Coli
  Product Introduction: AKR7A2 participates in the detoxification of aldehydes and ketones. AKR7A2 catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. AKR7A2 is involved in producing the neuromodulator gamma-hydroxybutyrate (GHB). AKR7A2 has extensive substrate specificity. AKR7A2 shows NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). AKR7A2 reduces 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). AKR7A2 reduces the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. AKR7A2 takes part in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
  Product Description: ALDOA Human Recombinant fused to 20 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 384 amino acids (1-364 a.a.) and having a molecular mass of 41.5 kDa. The ALDOA is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: ALDOA Recombinant Human although stable at 4C for 30 days, should be stored desiccated below -20C for periods greater than 30 days. Please avoid freeze-thaw cycles.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Peptide Sequence: MGSSHHHHHH SSGLVPRGSH MPYQYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE NTEENRRFYR QLLLTADDRV NPCIGGVILF HETLYQKADD GRPFPQVIKS KGGVVGIKVD KGVVPLAGTN GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKIGEHTPS ALAIMENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HIYLEGTLLK PNMVTPGHAC TQKFSHEEIA MATVTALRRT VPPAVTGITF LSGGQSEEEA SINLNAINKC PLLKPWALTF SYGRALQASA LKAWGGKKEN LKAAQEEYVK RALANSLACQ GKYTPSGQAG AAASESLFVS NHAY.

Target Info

• Gene Symbol: ALDOA
• Alias Symbols: ALDA, GSD12, HEL-S-87p
• NCBI Gene Id: 226
• Protein Name: Fructose-bisphosphate aldolase A
• Description of Target: Recombinant Human Aldolase-A
• Uniprot ID: P04075
• Protein Accession #: NP_000025.1
• Protein Size (# AA): Recombinant