Size:100 ug
$315.00
In Stock
SKU
OACA02419
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More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application WB, IHC, CHIP
Reconstitution and Storage Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement Item This antibody may replace item sc-135829, HPA002891
Immunogen Recombinant human RAC-alpha serine/threonine-protein kinase protein
Purification Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence Human
Datasheets/Manuals Printable datasheet for anti-AKT1 (OACA02419) antibody
Specificity Human
Formulation Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference [1] Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. Jones P.F., Jakubowicz T., Pitossi F.J., Maurer F., Hemmings B.A.Proc. Natl. Acad. Sci. U.S.A. 88:4171-4175 (1991)
Gene Symbol AKT1
Official Gene Full Name v-akt murine thymoma viral oncogene homolog 1
Alias Symbols AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA
NCBI Gene Id 207
Protein Name RAC-alpha serine/threonine-protein kinase
Description of Target The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
Swissprot Id P31749
Protein Accession # NP_001014431.1
Nucleotide Accession # NM_001014431.1
Protein Size (# AA) 480
Molecular Weight 56 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express AKT1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express AKT1.
  1. What is the species homology for "AKT1 Antibody (OACA02419)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "AKT1 Antibody (OACA02419)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "AKT1 Antibody (OACA02419)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "AKT1 Antibody (OACA02419)"?

    This target may also be called "AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA" in publications.

  5. What is the shipping cost for "AKT1 Antibody (OACA02419)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "AKT1 Antibody (OACA02419)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "AKT1 Antibody (OACA02419)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "56 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "AKT1 Antibody (OACA02419)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "AKT1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "AKT1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "AKT1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "AKT1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "AKT1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "AKT1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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