AKR1C2 Antibody - middle region (OASG02106)

Catalog No: OASG02106

Size:100 uL

Western Blot using COLO205

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human DD2. Location: 40-120aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: DD2 Polyclonal Antibody detects endogenous levels of DD2 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Target Info

• Gene Symbol: AKR1C2
• Gene Full Name: aldo-keto reductase family 1, member C2
• Alias Symbols: DD, DD2, TDD, BABP, DD-2, DDH2, HBAB, HAKRD, MCDR2, SRXY8, DD/BABP, AKR1C-pseudo
• NCBI Gene Id: 1646;
• Description of Target: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
• Uniprot ID: P52895
• Molecular Weight: 37 kDa