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Catalog No: OAGA00409
Size:100 ul
Price: $372.00
SKU
OAGA00409
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-AKR1C1 antibody - OAGA00409
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid 1XPBS, 20% glycerol (pH 7) with 0.025% Proclin300 added as a preservative
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationICC, IF, IHC-P, WB
Reconstitution and StorageKeep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze/thaw cycles.
ImmunogenRecombinant protein encompassing a sequence within the center region of human AKR1C1. The exact sequence is proprietary.
PurificationPurified by antigen-affinity chromatography.
Predicted Homology Based on Immunogen SequencePig, Rhesus Monkey(>80% identity)
ConcentrationVaries by lot. See vial for concentration.
Application InfoWB: 1:500~3000
ICC/IF: 1:100~1000
IHC-P: 1:100~1000
Publications

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity. Front Endocrinol (Lausanne). 11, 599869 (2021). 33584538

Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing. Sci Rep. 9, 10457 (2019). 31320667

Description
Gene SymbolAKR1C1
Gene Full NameAldo-keto reductase family 1 member C1
Alias SymbolsC9, DD1, DDH, DDH1, H-37, HBAB, MBAB, HAKRC, DD1/DD2, 2-ALPHA-HSD, 20-ALPHA-HSD
NCBI Gene Id1645
Protein NameAldo-keto reductase family 1 member C1
Description of TargetThis gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Uniprot IDQ04828
Protein Accession #NP_001344.2
Molecular Weight37 kDa
  1. What is the species homology for "AKR1C1 Antibody (OAGA00409)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "AKR1C1 Antibody (OAGA00409)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "AKR1C1 Antibody (OAGA00409)" provided in?

    This item is provided in "Liquid 1XPBS, 20% glycerol (pH 7) with 0.025% Proclin300 added as a preservative".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "AKR1C1 Antibody (OAGA00409)"?

    This target may also be called "C9, DD1, DDH, DDH1, H-37, HBAB, MBAB, HAKRC, DD1/DD2, 2-ALPHA-HSD, 20-ALPHA-HSD" in publications.

  5. What is the shipping cost for "AKR1C1 Antibody (OAGA00409)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "AKR1C1 Antibody (OAGA00409)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "AKR1C1 Antibody (OAGA00409)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "37 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "AKR1C1 Antibody (OAGA00409)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "AKR1C1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "AKR1C1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "AKR1C1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "AKR1C1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "AKR1C1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "AKR1C1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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