Aipl1 Antibody (OAPB00772)

Catalog No: OAPB00772

Size:100UG

Western blot analysis of Aipl1 in human brain tissue lysate with Aipl1 antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry of Aipl1 in human brain tissue with Aipl1 antibody at 2.5 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. Aipl1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: Aipl1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: Aipl1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Aipl1. The immunogen is located within amino acids 290 - 340 of Aipl1.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-Aipl1 antibody is Catalog # OEPB02892
• Application Info: Aipl1 antibody can be used for detection of Aipl1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Sohocki MM, Brown SJ, Sullivan LS, et al. Mutations in a new photoreceptor-pineal gene on 17p cause Leber congenital amaurosis. Nat. Genet.2000; 24:79-83.;Ma Q and Whitlock JP Jr. A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin. J. Biol. Chem.1997; 272:8878-84.;Hidalgo-de-Quintana J, Evans RJ, Cheetham ME, et al. The Leber congenital amaurosis protein aipl1 functions as part of a chaperone complex. Invest. Ophthalmol. Vis. Sci.2008; 49:2878-87.;Akey DT, Zhu X, Dyer M, et al. The inherited blindness associated protein Aipl1 interacts with the cell cycle regulator protein NUB1. Hum. Mol. Genet.2002; 11:2723-33.

Target Info

• Gene Symbol: AIPL1
• Gene Full Name: aryl hydrocarbon receptor interacting protein like 1
• Alias Symbols: AIPL2;aryl-hydrocarbon-interacting protein-like 1;LCA4.
• NCBI Gene Id: 23746
• Protein Name: Aryl-hydrocarbon-interacting protein-like 1|aryl-hydrocarbon-interacting protein-like 1 isoform 1 [Homo sapiens]
• Description of Target: May be important in protein trafficking and/or protein folding and stabilization.
• Uniprot ID: Q9NZN9
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_055151